Research

UPDATE with comments from interviw with CDC Director Tom Frieden.   Scroll below.

huffingtonpost.com - October 2nd, 2014 - Jeffery Young

The world has known about Ebola for almost 40 years, yet there's no cure or vaccine on the market.

That could change amid worldwide attention to the ongoing outbreak of the virus in West Africa, which has claimed more than 3,000 lives already, and the first diagnosis of a patient with the disease in the United States. But not for a few more years -- at least.

(VIEW COMPLETE ARTICLE)

Update: Comments by CDC Director on Sunday TV interview

http://www.nbcnews.com/storyline/ebola-virus-outbreak/cdc-director-tom-frieden-ebola-drug-pipeline-will-be-slow-n218666

nbcnews.com

A medical missionary recovering from Ebola infection in Nebraska was given an experimental drug made by a Canadian company, his doctors said Monday. They’d already said that Dr. Rick Sacra got transfusions of serum from recovered Ebola patient Dr. Kent Brantly. They also had revealed that he got a weeklong treatment course of an experimental drug but had not said what drug it was.

http://www.nbcnews.com/storyline/ebola-virus-outbreak/doctor-recovering-ebola-got-experimental-tekmira-drug-n209191

The Washington Post Follow-up to the original CNN report        Oct. 2, 2014

Since the original CNN interview, Logan has been in contact with Dr. Fauci. "I can't say it's a good idea or bad idea," Fauci told The Post this week. "It's one of those things where you're in a situation where you have no therapy, so you look for things that might be available."

Fauci said National Institutes of Health researchers have tested lamivudine's reaction to Ebola in test tubes. There was no response; but Fauci said researchers will adjust some levels and try it again "to see if there's even slight activity against Ebola."

If there is, he said, NIH would consider going to the trial stage.

It makes sense to consider lamivudine as a potential Ebola treatment: It belongs to a group of drugs known as nucleoside analogs, which interfere with the replication processes of certain viruses, Fauci explained.

See Washington Post report

http://www.washingtonpost.com/news/to-your-health/wp/2014/10/02/a-liberian-doctor-is-using-hiv-drugs-to-treat-ebola-victims-the-nih-is-intrigued/

Washington Post

by Abby Ohlheiser September 23 at 11:45 AM

London based scientists, working with international aid groups, are planning to start the first clinical trials in West Africa for drugs to treat Eboa. The trials could begin in a matter of months.

Wellcome Trust's $5 million initiative will include drugs from Mapp Biopharmaceutical, Sarepta and Tekmira, according to Reuters. Mapp makes zMapp, the experimental cocktail administered to two Americans who contracted the disease in Liberia. Tekmira recently gained the approval of the U.S. Food and Drug Administration to use its TKM-Ebola treatment on confirmed or suspected cases of the disease.

Both drugs are still in the experimental phase; researchers have not yet determined the safety or effectiveness of the treatments.

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