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Hurricanes, Droughts, and Wildfires: How Biopharma is Girding for Climate Change

           

A runner tries to navigate a flooded section of sidewalk underneath the Longfellow Bridge in Cambridge, Mass.  Jessica Rinaldi/The Boston Globe

statnews.com - by Kate Sheridan - February 15, 2019

. . . the potential risks of climate change — and the attendant increase in natural disasters — stand to outstrip any … incremental gains, as the companies described in recent risk assessment reports to the British nonprofit CDP.

Hurricanes and superstorms, power outages and flooding all threaten manufacturing facilities and research sites, particularly when animals are involved. Droughts, too, threaten critical water supplies. Forest fires, even if remote from a given plant or research facility, bring smoke and air pollution that can similarly disrupt the day-to-day work for drug makers and their supply chain . . .

. . . STAT surveyed the risk assessment plans for more than a dozen major pharmaceutical companies and spoke with officials at labs that survived extreme weather events and others who are planning to avoid their repercussions. All emphasized that the risks are already real — and underscored how hard the industry is working to prepare to meet the challenge.

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Animal Viruses: New Model Predicts Which May Spread Among Humans

CLICK HERE - STUDY - Transmissibility of emerging viral zoonoses

outbreaknewstoday.com - November 21, 2018

Researchers have developed a model that predicts which of the viruses that can jump from animals to people can also be transmitted from person to person–and are therefore possible sources of human diseases.

The study, published recently in PLOS One, identified several viruses that are not yet known to spread among humans but may have that potential, suggesting possible targets for future disease surveillance and research efforts.

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ALSO SEE RELATED ARTICLE HERE - Pub Med - Transmissibility of emerging viral zoonoses

 

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World's Vertebrate Population Dropped by an Average of 60 Percent Since 1970, WWF Says

CLICK HERE - WWF - Living Planet Report 2018: Aiming Higher

"There cannot be a healthy, happy and prosperous future for people" without biodiversity, the report warns.

nbcnews.com - by Rachel Elbaum - October 30, 2018

The population of the planet's vertebrates has dropped an average of 60 percent since 1970, according to a report by the WWF conservation organization.

The most striking decline in vertebrate population was in the tropics in South and Central America, with an 89 percent loss compared to 1970. Freshwater species have also significantly fallen — down 83 percent in that period.

The Living Planet Index, provided by the Zoological Society of London (ZSL) and included in the WWF Living Planet 2018 report, tracked the population of mammals, birds, fish, reptiles and amphibians around the world between 1970 and 2014, the latest year for which data was available.

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Outbreak of African Swine Fever Threatens to Spread from China to Other Asian Countries

           

There is no effective vaccine to protect swine from the disease.

FAO urges regional collaboration including stronger monitoring and preparedness measures

fao.org - August 28, 2018

The rapid onset of African Swine Fever (ASF) in China, and its detection in areas more than one thousand kilometres apart within the country, could mean the deadly pig virus may spread to other Asian countries anytime, the UN's Food and Agriculture Organization (FAO) warned today. 

There is no effective vaccine to protect swine from the disease. And, while the disease poses no direct threat to human health, outbreaks can be devastating with the most virulent forms lethal in 100 percent of infected animals.

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ALSO SEE RELATED ARTICLE HERE - 'It’s not if, it’s when': the deadly pig disease spreading around the world

 

 

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The World Bank - Operational Framework for Strengthening Human, Animal and Environmental Public Health Systems at Their Interface

                                                 

documents.worldbank.org - 29 January 2018

Abstract

Public health systems have critical and clear relevance to the World Bank’s twin goals of poverty eradication and boosting shared prosperity. In particular, they are impacted by, and must respond to,significant threats at human-animal-environment interface. Most obvious are the diseases shared between humans and animals (“zoonotic” diseases), which comprise more than 60 percent of known human infectious pathogens; but also aspects of vector-borne disease, food and water safety and security, and antimicrobial resistance. Public health systems must therefore be resilient and prepared to face existing and future disease threats at the human-animal-environment interface. the Operational Framework provides a strong orientation to One Health to assist users in understanding and implementing it, from rationale to concrete guidance for its application. Six core chapters are included, supported by annexes diving deeper into operational tools and recent World Bank alignment with One Health topics, and a glossary that explains key terms, including interpretations specific to the Operational Framework.

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Bat Cave Solves Mystery of Deadly SARS Virus — and Suggests New Outbreak Could Occur

           

Researchers analysed strains of SARS virus circulating in horseshoe bats, such as this one (Rhinolophus sinicus), in a cave in Yunnan province, China.  Credit: Libiao Zhang/Guangdong Institute of Applied Biological Resource

Chinese scientists find all the genetic building blocks of SARS in a single population of horseshoe bats.

CLICK HERE - RESEARCH - Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus

nature.com - by David Cyranoski - December 1, 2017

After a detective hunt across China, researchers chasing the origin of the deadly SARS virus have finally found their smoking gun. In a remote cave in Yunnan province, virologists have identified a single population of horseshoe bats that harbours virus strains with all the genetic building blocks of the one that jumped to humans in 2002, killing almost 800 people around the world. 

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Earth's Sixth Mass Extinction Event Under Way, Scientists Warn

Researchers talk of ‘biological annihilation’ as study reveals billions of populations of animals have been lost in recent decades

           

Earth already in midst of sixth mass extinction, scientists say

CLICK HERE - RESEARCH - PNAS - Biological annihilation via the ongoing sixth mass extinction signaled by vertebrate population losses and declines

theguardian.com - by Damian Carrington - July 10, 2017

A “biological annihilation” of wildlife in recent decades means a sixth mass extinction in Earth’s history is under way and is more severe than previously feared, according to research.

Scientists analysed both common and rare species and found billions of regional or local populations have been lost . . . 

 . . . “All signs point to ever more powerful assaults on biodiversity in the next two decades, painting a dismal picture of the future of life, including human life” . . . 

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Uptick in Creutzfeld-Jakob Cases Raises Questions

Is chronic wasting disease in deer making the jump to humans?

medpagetoday.com - by MedPage Today Staff - July 10, 2017

Cases of Creutzfeldt-Jakob disease, the fatal prion disease that's closely related to "mad cow" disease, have risen in Wisconsin and nationally in recent years, according to the Milwaukee Journal Sentinel.

In Wisconsin, there were six cases in 2002, but in two of the last four years, 13 cases have been reported -- which could be attributed to better surveillance, local officials said. Yet the increase tracks with data on chronic wasting disease among deer in the state, raising concerns about whether the illness is jumping from animals to humans.

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CLICK HERE - Milwaukee Journal Sentinel - Can chronic wasting disease jump from deer to humans? Concerns keep rising

 

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Brazil Yellow Fever Outbreak Spawns Alert: Stop Killing the Monkeys

Yellow fever is threatening species at risk of extinction, like the golden lion tamarin, which lives in the forests of Rio de Janeiro State. Credit Dado Galdieri for The New York Times

Image: Yellow fever is threatening species at risk of extinction, like the golden lion tamarin, which lives in the forests of Rio de Janeiro State. Credit Dado Galdieri for The New York Times

nytimes.com - May 2nd 2017 - Simon Romero

As fears spread in Brazil over the resurgence of yellow fever, health officials are issuing a warning: Stop killing the monkeys.

Some assailants clubbed monkeys to death in panicked reactions to Brazil’s most alarming outbreak in decades of a virus that haunted the country in the 19th and early 20th centuries. Authorities found other monkeys dead with fractured skulls after having been being attacked with stones. 

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Why Chinese Scientists Are More Worried Than Ever About Bird Flu

A shop owner holds a live chicken for sale in a Hong Kong market. Isaac Lawrence /AFP/Getty Images

Image: A shop owner holds a live chicken for sale in a Hong Kong market. Isaac Lawrence /AFP/Getty Images

npr.org - April 11th 2017 - Rob Schmitz

At a research lab on top of a forested hill overlooking Hong Kong, scientists are growing viruses. They first drill tiny holes into an egg before inoculating it with avian influenza to observe how the virus behaves.

This lab at Hong Kong University is at the world's forefront of our understanding of H7N9, a deadly strain of the bird flu that has killed more people this season — 162 from September up to March 1 — than in any single season since when it was first discovered in humans four years ago. 

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