Vaccines Could Blunt U.K. Epidemic in Weeks

LONDON — Britain is on a pace to give the first shot of a two-dose coronavirus vaccine to its entire population by the end of June, if it can avoid supply and logistical issues that threaten to slow one of the world’s fastest rollouts.

The most vulnerable will get their first doses much sooner — likely over the next two weeks — which could drastically reduce deaths. People over 70, nursing home residents and workers, health and social workers, and those whose health problems make them extremely vulnerable are all on schedule to receive their first vaccine shots before Feb. 15. Together these groups have accounted for 88 percent of all Covid-19 deaths.

The timeline shows the promise of vaccination as a path out of the deadliest stage of the pandemic in the countries that are moving quickly. ...

Vaccine found 92% effective in Israel, in first controlled result outside trials Only 31 out of 163,000 fully vaccinated Maccabi members caught virus, indicating Pfizer shots living up to expectations; expert: Results 'well within expected standard deviation' timesofisrael

Pfizer’s coronavirus vaccine is showing 92 percent effectiveness in Israel, according to the world’s first big controlled investigation on how it works outside of clinical tests.

https://www.theguardian.com/world/2021/jan/19/single-covid-vaccine-dose-in-israel-less-effective-than-we-hoped

Israel’s coronavirus tsar has warned that a single dose of the Pfizer/BioNTech vaccine may be providing less protection than originally hoped, as the country reported a record 10,000 new Covid infections on Monday.

In remarks reported by Army Radio, Nachman Ash said a single dose appeared “less effective than we had thought”, and also lower than Pfizer had suggested.

By contrast, those who had received their second dose of the Pfizer vaccine had a six- to 12-fold increase in antibodies, according to data released by Sheba Medical Center in Tel Hashomer on Monday.